Tag: diphenhydramine

First-Generation Antihistamines: Why Severe Drowsiness and Anticholinergic Effects Matter

First-Generation Antihistamines: Why Severe Drowsiness and Anticholinergic Effects Matter
Jan, 4 2026 Keaton Groves

First-generation antihistamines like Benadryl cause severe drowsiness and anticholinergic side effects that can last all day. Learn why they're risky, who should avoid them, and what safer alternatives exist.